CHARACTERIZATION OF 3-HYDROXYISOBUTYRYL-COA HYDROLASE (HIBCH) DEFICIENCY IN BAHRAIN: A RETROSPECTIVE COHORT STUDY

Characterization of 3-Hydroxyisobutyryl-Coa Hydrolase (HIBCH) Deficiency in Bahrain: A Retrospective Cohort Study

Background: 3-Hydroxyisobutyryl-CoA hydrolase (HIBCH) deficiency is a rare inborn error of valine catabolism associated with progressive neurological impairment.This retrospective cohort study aimed to characterize the clinical, biochemical, genetic, and respiratory chain profiles of HIBCH deficiency patients in Bahrain.Methods: Eight HIBCH deficie

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Stoichiometrically Governed Curcumin Solid Dispersion and Its Cytotoxic Evaluation on Colorectal Adenocarcinoma Cells

Jamal Moideen Muthu Mohamed,1 Ali Alqahtani,2 Fazil Ahmad,3 V Krishnaraju,2 K Kalpana4 1Department of Pharmaceutical Technology, BIT Campus, Anna University, Tiruchirappalli, Tamil Nadu 620024, India; 2Department of Pharmacology, College of Pharmacy, King Khalid University, Guraiger, Abha 62529, Saudi Arabia; 3Department of Anesthesia Technology, C

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Observations of wave run-up affected by dune scarp during storm conditions: a two dimensional large-scaled movable bed experiment

Artificial dunes serve as essential nature-based defenses against the increasing threats posed by climate change and rising sea levels along coastal regions.However, these man-made dunes are particularly susceptible to erosion during severe storm events, necessitating careful consideration of their design for effective coastal protection.Among the

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